Cefapirina [INN-Spanish]
Brand names,
Cefapirina [INN-Spanish]
Analogs
Cefapirina [INN-Spanish]
Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefapirina [INN-Spanish]
Chemical_Formula
C17H17N3O6S2
Cefapirina [INN-Spanish]
RX_link
No information avaliable
Cefapirina [INN-Spanish]
fda sheet
Cefapirina [INN-Spanish]
msds (material safety sheet)
Cefapirina [INN-Spanish]
Synthesis Reference
No information avaliable
Cefapirina [INN-Spanish]
Molecular Weight
423.466 g/mol
Cefapirina [INN-Spanish]
Melting Point
No information avaliable
Cefapirina [INN-Spanish]
H2O Solubility
1030 mg/L
Cefapirina [INN-Spanish]
State
Solid
Cefapirina [INN-Spanish]
LogP
-0.251
Cefapirina [INN-Spanish]
Dosage Forms
Gel; Suspension
Cefapirina [INN-Spanish]
Indication
For treatment of infections caused by susceptible bacteria.
Cefapirina [INN-Spanish]
Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefapirina [INN-Spanish]
Absorption
No information avaliable
Cefapirina [INN-Spanish]
side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefapirina [INN-Spanish]
Patient Information
No information avaliable
Cefapirina [INN-Spanish]
Organisms Affected
Enteric bacteria and other eubacteria